New Orleans, Louisiana, USA with the Crescent City Connection Bridge on the Mississippi river and downtown New Orleans Louisiana taken at sunset.
f11photo/Shutterstock.com

Road Trip from Charleston, SC to New Orleans

Updated by Pat Dorri on March 1 2024

Get ready to experience Southern charm and hospitality on this road trip from historic Charleston to New Orleans, where music, cuisine and dazzling festivities converge. Along the way, you'll experience a diverse landscape that includes lots of natural beauty and vibrant cities.

The 790-mile road trip from Charleston to New Orleans will take 12 hours to drive. Highlights include Augusta, Atlanta, Birmingham, Meridian and Hattiesburg, as well as Talladega, Chattahoochee-Oconee, De Soto National Forests and Bonita Lakes Park.

We have compiled the must-see sites and the finest overnight stops on this fantastic Southern adventure. So, read on to find out all you need to know, including the best times of the year to plan your road trip between Charleston and New Orleans.

How far is New Orleans from Charleston, SC, and how long will the road trip take?

Comparison of road trip routes between Charleston, SC to New Orleans
RouteDistanceDriving Time
The Inland Route790 miles12 hours 20 minutes
The Coastal Route850 miles16 hours

There are two great options for the road trip from Charleston, SC to New Orleans. The Inland Route is shorter, covering 790 miles and taking around 12 hours and 20 minutes to drive directly.

If you want to add some beach vibes to your road trip, opt for the Coastal Route. This covers 850 miles and takes a minimum of 16 hours to drive without stops.

There is so much to see and do on these routes, you will likely want to take three or four days to explore. This is especially true if you want to spend time on the beautiful beaches of Northern Florida and Mississippi.

Savannah, Georgia, USA with a row of bars and restaurants on River Street at twilight with street lights and trees on the other side.
Pretty River Street in Savannah, Georgia showcasing some of the great bars and restaurants you can find in this great city.Sean Pavone/Shutterstock.com

Best road trip route from Charleston, SC to New Orleans

There is plenty to recommend on both the Inland and Coastal routes on a Charleston, SC to New Orleans road trip, so whichever you choose, you are guaranteed a road trip to remember.

Which of the routes you opt for will ultimately depend on the time you have for your trip and on whether you want to enjoy any time at the beach during your travels.

The Inland Route does not feature any beaches along the way, while the Coastal Route traces the stunning Gulf of Mexico and is dominated by a coastal landscape.

The Inland Route is great if you want to discover some of the finest cities of the South, such as Atlanta and Birmingham, as well as some spectacular national forests.

On the other hand, the Coastal Route takes in some of the country's loveliest beaches including Gulf Shores, Panama City Beach, and Pensacola, and characterful Southern cities, such as Savannah and Jacksonville.

Whether you're flying into Charleston, SC, or you simply don't have your own transport in the city, renting a car for your road trip is something you'll want to take care of ASAP.

For an easy-to-compare view of rental options for your road trip from Charleston, SC, to New Orleans, take a look at our partner site, RentalCars.com.

How to drive from Charleston, SC to New Orleans

The map above shows our suggestions for the best road trip routes between Charleston, SC and New Orleans. Keep reading for detailed descriptions of both routes, where to stay on either, and the best things to do on the way.

The Inland Route

Leave Charleston via Interstate-26 (I-26) West and head towards Augusta, Georgia. Following I-20 from here will get you directly into Atlanta, where you can take a break to explore.

Your next stop will be the musical city of Birmingham, Alabama. After spending some time here, head southwest into Mississippi. The interstate and US-11 will lead you into Hattiesburg. You can make a detour here to visit De Soto National Forest.

If not, you will soon reach the colorful city of New Orleans following the interstate southwest.

Birmingham, Alabama, USA with the city skyline of Birmingham from Railroad Park in the distance and the water reflecting the buildings in the foreground.
One of the many cities you can pass on this epic road trip, Birmingham, Alabama is home to pretty parks and fascinating museums.ESB Professional/Shutterstock.com

The Coastal Route

Leave Charleston via US-17 South and head towards Savannah. Take a break here to admire the beautiful buildings and historic landmarks before setting off northwest to reach Jacksonville, Florida.

Driving west through the state will get you to Tallahassee. Follow US-231 and continue towards Panama City Beach. After taking a break and dipping your toes in sand here, you can go beach hopping in Destin.

This route will take you from one gorgeous coastal city to another-your next stops will be Pensacola and Gulf Shores. Hop onto I-10 to visit Mobile. Make sure to visit USS ALABAMA Battleship Memorial Park here before heading towards Biloxi Beach.

Hugging the shore of the Gulf of Mexico, you will soon reach downtown New Orleans.

Mobile Bay, USA with the shoreline at late afternoon evening, with the pier in the background and a fallen tree in the foreground.
Make a stop at Mobile Bay on the Coastal Route to New Orleans for great views and pretty buildings.Captainess_travels/Shutterstock.com

Best places to stop between Charleston, SC and New Orleans

While both the road trip routes between Charleston and New Orleans are just about drivable in a day, we certainly recommend making some stops along the way.

Here are our favorite overnight stops on each route, with suggestions for where to stay, plus a great choice for a hotel once you've reached your destination.

Enjoy the vibrant colors of Atlanta

Located about five hours from Charleston on the Inland Route, the city of Atlanta is ideal for an overnight stop that offers plenty to see and do. With its rich history and cultural attractions, you might even find one night is not enough in this cosmopolitan city.

Atlanta, Georgia, USA downtown skyline taken at night with the skyscrapers lit up in the background.
Stunning Atlanta is a great overnight stop on the Inland Route thanks to its rich history and beautiful botanical gardens.Sean Pavone/Shutterstock.com

While you're here, be sure to pay a visit to Atlanta Botanical Garden with its living sculptures. You can also learn more about one of the world's most popular beverages at World of Coca-Cola.

Centrally located in downtown, The Candler Hotel Atlanta, Curio Collection by Hilton is an excellent option for an overnight stay. This beautiful hotel boasts a stellar location, which means that you can take a real break from the road and explore on foot.

With Georgia Aquarium and Centennial Olympic Park just two of the nearby attractions, you will have plenty to do on your day out exploring. There will never be a dull moment as the city is also renowned for its inspirational street art.

After grabbing a beer at one of the famous breweries that line the city, you can head back to the stylish hotel, where you can sit down to a meal at the upscale restaurant, sip a drink at the fabulous bar, and take advantage of the attentive concierge service.

Before you hit the road again in the morning, you can enjoy a hearty breakfast at the hotel that's sure to fuel you for the next leg of your journey.

READ MORE - Click here for more great hotel options

Relax on the beach in Panama City Beach

If you choose the Coastal Route, we think Panama City Beach in Northwest Florida is a great overnight stop on your road trip. Located about five hours by road from New Orleans, it's the ideal place to chill out and relax before you reach your fun-filled final destination.

Panama City Beach, USA with a beach and ocean view from edgewater taken just before sunset.
Get your beach vibes with a stop at iconic Panama City Beach - the perfect blend of city amenities and white sandy beaches.Pendaran Roberts/Shutterstock.com

Of course, Panama City Beach is most famous for – yes, you guessed it – its beautiful sandy beaches! While you're here, be sure to visit the Pier Park shopping and entertainment area. You might also like to take one of the whale-watching or catamaran cruises.

Make the most of the lovely location by choosing a hotel that's right on the beach, such as SpringHill Suites by Marriott Panama City Beach Beachfront.

As well as offering direct access to the beach, the all-suites hotel features a fantastic outdoor swimming pool. There is also a superb restaurant on-site.

If you want a break from the beach, Shipwreck Island, Gulf World Marine Park and Ripley's Believe it or Not! are among the attractions in the area.

Where to stay when you reach New Orleans

There is so much to enjoy in New Orleans, from the omnipresent live jazz and Creole cuisine to the colorful cultural highlights and diverse history.

New Orleans, Louisiana, USA taken at Jackson Square and St. Louis Cathedral on a sunny day with palm trees in the foreground.
As well as its famous jazz scene, New Orleans has architecturally beautiful buildings, including the St. Louis Cathedral on Jackson Square.Sean Pavone/Shutterstock.com

Make the most of your time in the so-called “Big Easy” by choosing a central hotel that's a great base for exploring this walkable city.

Located in the famous French Quarter, One11 is a chic hotel just a short distance from Bourbon Street, a historic thoroughfare known for its lively music joints and restaurants.

You can also find the Aquarium of the Americas and Harrah's Casino in the vicinity. When you want to take a break from sightseeing, the hotel features a fantastic restaurant and bar, a beautiful swimming pool, and a glorious sun terrace.

Things to see on a road trip from Charleston, SC to New Orleans

The Inland Route and Coastal Route offer distinct itineraries with plenty of great stops along the way. To help you plan your journey, we've picked out some of the highlights of both road trip routes from Charleston to New Orleans.

Augusta, Georgia, USA taken at downtown with the city skyline in the background and boats on the river in the foreground, taken on a clear sunny day.
You can still get your waterside fix with a stop at Augusta in Georgia, which is also home to the Canal Discovery Center.Sean Pavone/Shutterstock.com

The Inland Route

  1. Aiken County Historical Museum, South Carolina - Discover the area's fascinating history at this living museum housed in a charming "Winter Colony" cottage and set in lovely grounds.
  2. Augusta, Georgia - Home to The Masters Golf Tournament, the city has plenty more to enjoy, including Augusta Canal Discovery Center and Augusta Museum of History.
  3. Chattahoochee-Oconee National Forest, Georgia - Great for biking, hiking, and horse riding, or more gentle outdoor pursuits, this stunning national forest is the perfect place to spend a peaceful afternoon.
  4. Talladega National Forest, Alabama - Discover even more natural beauty at this stunning forest, which is home to Cheaha Falls and Cheaha Lake.
  5. Birmingham, Alabama - Founding city of Veterans' Day, you can also visit the Barber Vintage Motorsports Museum and Birmingham Civil Rights Institute.
  6. UpSurge Trampoline Park, Alabama - The young and young at heart can enjoy a few fun hours bouncing around at this Tuscaloosa attraction.
  7. Bonita Lakes Park, Mississippi - Take a break from the road at this lakeside park, which is also great for watersports.
  8. De Soto National Forest, Mississippi - Explore another of this region's most awe-inspiring natural sites, named for 16th-century Spanish explorer Hernando de Soto.
Jacksonville, Florida, USA wit the city skyline in the background and the fountain lit up at night in the foreground.
The Coastal Route takes you through Jacksonville, a charming city with great museums, restaurants and a stunning fountain that's especially beautiful at night.Sean Pavone/Shutterstock.com

The Coastal Route

  1. Savannah, Georgia - Discover the striking architecture and interesting history of this Southern city, which is also home to Forsyth Park.
  2. Parris Island Museum, South Carolina - Located on a Marine base, this museum brings to life the history of the United States Marine Corps.
  3. Jacksonville, Florida - Enjoy the natural beauty and wildlife of this charming city, which is also home to the Museum of Science and History and Jacksonville Arboretum and Gardens.
  4. Osceola National Forest, Florida - Spend a few hours exploring this peaceful forest, which is located to the west of Jacksonville.
  5. Tallahassee, Florida - Home to Florida State University, this characterful city features lots of interesting attractions, including Tallahassee Automobile Museum and the US' third tallest capitol building.
  6. Destin, Florida - More coastal beauty awaits in Destin, which is also home to Destin History & Fishing Museum and Destin Harbor Boardwalk and is a great place for dolphin-spotting.
  7. Mobile, Alabama - Take time to explore this renowned Gulf Coast cultural center, where you can also find the Battleship USS Alabama and Mobile Carnival Museum.
  8. Biloxi Beach, Mississippi - Seafood lovers, in particular, will love this resort, once known as the “Seafood Capital of the World”, with its shrimping trips and sunset cruises.
Destin, Florida, USA during morning sunrise with calm water and soft sand in the foreground.
For a stunning beach location, Destin in Florida awaits. Here you'll get white soft sandy and the chance to spot a dolphin.Jay Beckerich/Shutterstock.com

Best time to go on a road trip from Charleston, SC to New Orleans

One of the great things about this road trip is that you can enjoy it year-round. There is so much to see, indoors and out, as well as the benefits of the Southern US climate.

In Atlanta, winter temperatures only drop to around 50 to 55 degrees Fahrenheit, while September is the peak month for hurricanes in Louisiana.

New Orleans reaches around 90 degrees Fahrenheit in the summer. However, as summer is considered the off-peak season, if you don't mind the heat, you can grab a great deal on a hotel. We recommend booking early.

If you're planning to take the Coastal Route to enjoy some time at the beach, we would recommend avoiding the winter months. With temperatures at around 62 degrees Fahrenheit, it will likely be too chilly for sunbathing or taking a dip in the sea.

The peak season in New Orleans is spring, especially March, which sees the famous Mardi Gras festival. If you want to join in the fun of the Mardi Gras celebrations, be aware that the city will be extra busy during this time and prices will be higher than the rest of the year.

Other notable festivals in New Orleans include October's Crescent City Blues & BBQ Festival and the French Quarter Festival in April, so you are sure to have a fantastic time no matter when you choose to visit this iconic city!